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API (Commercialized)GMP/DMFAnimal Health / Ophthalmology

Lotilaner

Ectoparasite control in dogs and cats; ophthalmic use for demodex blepharitis

CAS No.
1369852-71-0
Indication Class
Animal Health
Patent Expiry
To be assessed
Therapeutic Area
Animal Health / Ophthalmology
Labeled Purity
98%+
Registration Readiness
GMP/DMF
Commercialization Tier
API (Commercialized)
Linked Intermediates
3 key intermediates available
Isoxazoline ClassCross-speciesHuman Ophthalmic Expansion

Key Intermediates for This API

Order: listed intermediates that accept enquiries first; fragments shared across several APIs rank higher
IntermediateCASSharedAction
2-bromo-3-methyl-5-acetylthiophene859199-06-7
5-acetyl-3-methyl-2-Thiophenecarboxylic acid2758907-91-2
methyl 5-acetyl-3-methylthiophene-2-carboxylate2758907-87-6

Listing Logic · Why It's Worth Listing

The only isoxazoline expanded into human ophthalmology (demodex blepharitis), combining a steady animal-health base with a human-use upside option.

Demand

Animal Health / Ophthalmology · Marketed; available for immediate sourcing

Compliance

GMP/DMF-ready; supports regulatory filing and audit in target markets

Supply

3 key intermediates available; scale-up and cost control manageable

Product Description

Lotilaner is an ectoparasiticide from the modern isoxazoline class, notable for its unique dual utility. While established in veterinary medicine, it has achieved a groundbreaking milestone as the first FDA-approved drug for a specific human eye condition.

Supply source: Unibest · Lotilaner, sourced, vetted and delivered by Unibest. Therapeutic area, indication and listing rationale are qualitative summaries based on public drug knowledge for business reference; actual registration availability and quality specifications are subject to DMF/GMP documentation and the technical agreement confirmed at order.