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Patent-Cliff Blockbusters & Intermediate Opportunities

2028–2033 patent cliff mapped from licensed Pharmacodia data, with actionable intermediate CAS lists

81
Drugs
19
Tier A — Act now
21
Tier B — Position early
41
Tier C — Watch / trade
1556
Intermediates
1301
Unique CAS
Download full list (Excel: drug tiers + intermediates)

Tier A — Act now (peak sales ≥ $3B, expiry 2028–2031)

DrugGeneric nameOriginatorFirst approvalExpiryPeak($B)StepsInterm.
阿哌沙班Apixaban百时美施贵宝2011202822.4▲69
司美格鲁肽（深圳翰宇）Semaglutide(Hybio Pharma)深圳翰宇药业股份有限公司-203118.4*-0
伊布替尼IbrutinibPharmacyclics Llc201320279.78▲811
恩扎卢胺Enzalutamide加州大学洛杉矶分校201220278.62▲57
利伐沙班Rivaroxaban拜耳200820267.89▲912
甲磺酸奥希替尼Osimertinib Mesylate阿斯利康201520317.25▲711
恩格列净EmpagliflozinBoehringer Ingelheim International Gmbh201420285.97▲811
磷酸芦可替尼Ruxolitinib PhosphateIncyte Corp201120285.88▲56
阿贝西利Abemaciclib礼来制药201720295.72▲913
达格列净丙二醇/盐酸二甲双胍Dapagliflozin Propanediol/Metformin Hydrochloride阿斯利康201420305.6*-0
哌柏西利Palbociclib辉瑞201520275.44▲913
琥珀酸瑞波西利Ribociclib Succinate诺华制药201720294.78▲914
奥拉帕利Olaparib阿斯利康201420284.73▲610
卡利拉嗪盐酸盐Cariprazine Hydrochloride吉瑞大药厂201520294.47▲521
泽布替尼Zanubrutinib百济神州有限公司201920313.93▲1012
阿帕他胺Apalutamide强生创新制药201820303.57▲1120
阿可替尼Acalabrutinib阿斯利康201720303.52▲811
甲磺酸仑伐替尼Lenvatinib Mesilate卫材株式会社201520283.34▲913
布瑞哌唑Brexpiprazole大冢制药株式会社201520293.15▲318

Intermediate breakdown (all drugs with retrieved synthetic routes, by intermediate count)

Key intermediate CAS numbers registered in Pharmacodia synthetic routes (originator + optimised routes) — ready for supplier sourcing and RFQ.

非奈利酮7 steps
Finerenone
CodeCAS No.
FINE-001959934-76-0
FINE-00221962-45-8
FINE-00365193-87-5
FINE-0041050477-39-8
FINE-00595306-64-2
FINE-0061050477-43-4
FINE-0071050477-44-5
FINE-0081050477-45-6
FINE-0091050477-27-4
(I)90859-10-a18368-64-4
(II)90859-10-a20173-49-3
(III)90859-10-a60323-96-8
(IV)90859-10-a79055-62-2
(VI)90859-10-a1663-67-8
(VII)90859-10-a107-12-0
(VIII)90859-10-a95306-65-3
(IX)90859-10-a41935-71-1
(X)90859-10-a1260663-96-4
(I)638294-1-a5394-63-8
(II)638294-1-a109-78-4
(V)638294-1-a1870824-80-8
(VIIIa)638294-1-a122-51-0
(VIIIb)638294-1-a,(VIIIb)638294-1-e78-39-7
(XII)638294-1-a2084136-51-4
(XIII)638294-1-b121-33-5
(XIV)638294-1-b4421-08-3
(XV)638294-1-b652997-57-4
(XVI)638294-1-b1663-39-4
(XVII)638294-1-b
(XVIII)638294-1-b72135-36-5
(XIX)638294-1-b139102-34-4
(XX)638294-1-b43192-33-2
(XXIV)638294-1-c,(XXIV)638294-1-d3556-60-3
(XXV)638294-1-c914106-35-7
(XXVI)638294-1-c104436-60-4
(XXVII)638294-1-c
(XXI)638294-1-c7151-68-0
(XXII)638294-1-c87808-44-4
(XXIII)638294-1-c1017082-75-5
(XXVIII)638294-1-d99-06-9
(XXIX)638294-1-d618-49-5
(XXX)638294-1-d873-62-1
(XXXI)638294-1-d50-00-0
(XXXII)638294-1-d84102-89-6
(XXXIII)638294-1-d77-78-1
(XXXIV)638294-1-d74-88-4
(XXXV)638294-1-d170572-49-3
(XXXVI)638294-1-d67-56-1
(XXXVII)638294-1-d176961-57-2
(XXXVIII)638294-1-d,(XXXVIII)638294-1-e120315-65-3
(XL)638294-1-e3092281-06-3
(XLI)638294-1-e
(XLII)638294-1-e2469-99-0
(XLIII)638294-1-e
(XXXIX)638294-1-e22163-77-5
(I)638294-2-a1666-28-0
(V)638294-2-a5977-14-0
(VI)638294-2-a2087452-79-5
(VII)638294-2-a2087452-80-8
(IX)638294-2-a2087452-81-9
(XIII)638294-2-a100-46-9
(XIV)638294-2-a61190-99-6
(II)638294-3-a75-03-6
(III)638294-3-a1545905-35-8
(IV)638294-3-a2569527-38-2
(VI)638294-3-a2569527-39-3
(VII)638294-3-a2569527-40-6
(A)638294-3-a
(XIII)638294-3-b
(XV)638294-3-b
(XVI)638294-3-b
(III)638294-4-a105-53-3
(IV)638294-4-a2764833-06-7
(VI)638294-4-a2764833-07-8
(VII)638294-4-a2764833-08-9
(VIII)638294-4-a2764833-09-0
(A)638294-4-a2135478-70-3
(IIa)638294-5-a61312-32-1
(IIb)638294-5-a5396-89-4
(IIc)638294-5-a1694-31-1
(IId)638294-5-a2974322-13-7
(IIe)638294-5-a174654-67-2
(IVa)638294-5-a
(IVb)638294-5-a
(IVc)638294-5-a
(IVd)638294-5-a
(IVe)638294-5-a
(VIa)638294-5-a
(VIb)638294-5-a2389020-00-0
(VIc)638294-5-a
(VId)638294-5-a
(VIe)638294-5-a
(VIIIa)638294-5-a
(VIIIb)638294-5-a,(VIIIb)638294-5-b
(VIIIc)638294-5-a
(VIIId)638294-5-a,(VIIId)638294-5-b
(IXa)638294-5-a
(IXb)638294-5-a
(IXc)638294-5-a
(IXd)638294-5-a
(IXe)638294-5-a
(X)638294-5-a,(X)638294-5-b2640506-74-5
(XIa)638294-5-a
(XIb)638294-5-a
(III)638294-6-a
(V)638294-6-a
(VI)638294-6-a
(VIII)638294-6-a
(IX)638294-6-a
(X)638294-6-a
(II)638294-7-a
(IV)638294-7-a
(VI)638294-7-a
(VII)638294-7-a110-71-4
(VIII)638294-7-a
(IX)638294-7-a
(II)638294-8-a
(IV)638294-8-a2640574-73-6
(VII)638294-8-a
(II)638294-9-a58547-15-2
(III)638294-9-a
(IV)638294-9-a
(VI)638294-9-a
(VIII)638294-9-a
(IX)638294-9-a
(II)638294-10-a,(II)638294-10-b105-45-3
(III)638294-10-a
(V)638294-10-a
(VII)638294-10-a
(VIII)638294-10-a
(IX)638294-10-a,(IX)638294-10-b
(XI)638294-10-b105942-10-7
(XII)638294-10-b
(XIII)638294-10-b
(XIV)638294-10-b
(XV)638294-10-b
(XVI)638294-10-b124-41-4
(II)638294-11-a22502-03-0
(III)638294-11-a
(V)638294-11-a
(VII)638294-11-a
(IX)638294-11-a
(X)638294-11-a
(XIb)638294-11-a
(I)638294-12-a56-45-1
(II)638294-12-a26348-61-8
(III)638294-12-a70930-18-6
(V)638294-12-a
(VII)638294-12-a
(IX)638294-12-a
(XI)638294-12-a
(XII)638294-12-a
(XIII)638294-12-a
(IIa)638294-13-a51719-12-1
(IIb)638294-13-a882-36-0
(IIIa)638294-13-a
(IIIb)638294-13-a
(Va)638294-13-a
(Vb)638294-13-a
(VIIa)638294-13-a
(VIIb)638294-13-a
(Xa)638294-13-a
(Xb)638294-13-a
(III)638294-14-a
(V)638294-14-a
(VI)638294-14-a
(VIII)638294-14-a
(IX)638294-14-a
(II)638294-15-a29816-98-6
(III)638294-15-a
(V)638294-15-a
(VII)638294-15-a
(I)638294-16-a165336-55-0
(IV)638294-16-a
(VI)638294-16-a
(VI)638294-17-a
(VII)638294-17-a
(IIa)638294-18-a61312-84-3
(IIb)638294-18-a61312-35-4
(IVa)638294-18-a
(IVb)638294-18-a
(VIa)638294-18-a
(VIb)638294-18-a
(VII)638294-18-a
(IXa)638294-18-a
(IXb)638294-18-a
(Xa)638294-18-a
(Xb)638294-18-a
(II)638294-19-a5470-11-1
(III)638294-19-a
(IV)638294-19-a
(II)638294-20-a
(III)638294-20-a
(IV)638294-20-a
(I)638294-21-a102029-44-7
(II)638294-21-a674-82-8
(III)638294-21-a
(V)638294-21-a
(VII)638294-21-a
(VIII)638294-21-a
(X)638294-21-a
(IIa)638294-22-a
(IIb)638294-22-a
(IIc)638294-22-a
(IIIa)638294-22-a
(IIIb)638294-22-a
(IIIc)638294-22-a
(Va)638294-22-a
(Vb)638294-22-a
(Vc)638294-22-a
(VIIa)638294-22-a
(VIIb)638294-22-a
(VIIc)638294-22-a
(VIIIa)638294-22-a
(VIIIb)638294-22-a
(VIIIc)638294-22-a
(II)638294-23-a
(III)638294-23-a
(I)473558-2-a121-34-6
(II)638294-24-a
(III)638294-24-a
普拉替尼8 steps
Pralsetinib
CodeCAS No.
(I)1024528-1-a,(I)1024528-1-d4746-97-8
(II)1024528-1-a2097133-36-1
(III)1024528-1-a1622928-67-9
(IV)1024528-1-a2097133-42-9
(V)1024528-1-a2097133-18-9
(VI)1024528-1-a89466-59-1
(VII)1024528-1-a5424-21-5
(VIII)1024528-1-a2742918-71-2
(IX)1024528-1-a2097133-29-2
(X)1024528-1-a,(X)1024528-1-d2097133-30-5
(XI)1024528-1-a,(XI)1024528-1-b2097133-31-6
(XII)1024528-1-b31230-17-8
(XIII)1024528-1-b2097133-32-7
(XIV)1024528-1-b2459966-45-9
(XIX)1024528-1-b,(XIX)1024528-1-c1980023-94-6
(XV)1024528-1-b139042-59-4
(XVa)1024528-1-b2097133-17-8
(XVb)1024528-1-b1980023-96-8
(XVc)1024528-1-b
(XVII)1024528-1-b,(XVII)1024528-1-c35277-02-2
(XVIII)1024528-1-b102-52-3
(XX)1024528-1-b196929-78-9
(XXI)1024528-1-b1980023-95-7
(XXII)1024528-1-c76-37-9
(XXIII)1024528-1-c343331-58-8
(XXIV)1024528-1-c1438425-76-3
(XXIX)1024528-1-c288-13-1
(XXV)1024528-1-c
(XXVI)1024528-1-c
(XXVII)1024528-1-c5341-61-7
(XXVIII)1024528-1-c
(XXX)1024528-1-c53939-30-3
(XXXI)1024528-1-c108-24-7
(XXXII)1024528-1-c55676-22-7
(XXXIII)1024528-1-d69947-09-7
(XXXIV)1024528-1-d1252690-12-2
(XXXV)1024528-1-d1252973-00-4
(XXXVI)1024528-1-d141-97-9
(XXXVII)1024528-1-d
(XXXVIII)1024528-1-d
(I)1024528-2-a14394-60-6
(II)1024528-2-a2675521-17-0
(IV)1024528-2-a2675521-16-9
(VI)1024528-2-a578008-32-9
(I)1024528-3-a,(I)1024528-3-b2778223-41-7
(II)1024528-3-a
(III)1024528-3-a
(IV)1024528-3-a105-45-3
(VI)1024528-3-a
(VIII)1024528-3-a
(IX)1024528-3-a
(XV)1024528-3-b34916-10-4
盐酸艾司氯胺酮3 steps
Esketamine Hydrochloride
CodeCAS No.
ESKE-0016740-88-1
ESKE-00287-69-4
ESKE-003199468-20-7
ESKE-00433643-46-8
ESKE-005615-41-8
ESKE-006108-94-1
ESKE-00791393-49-6
ESKE-008870-50-8
ESKE-0091668563-29-8
ESKE-01083777-65-5
(I)270899-1-a6740-85-8
(II)270899-1-a1823362-29-3
(III)270899-1-a
(V)270899-1-a33795-24-3
(VIa)270899-1-a33643-49-1
(VIb)270899-1-a
(VIc)270899-1-a
(VId)270899-1-a
(IV)270899-2-a
(VI)270899-2-a,(VI)270899-2-c
(VII)270899-2-a2375682-62-3
(VIII)270899-2-a50-00-0
(X)270899-2-b
(XI)270899-2-b820217-06-9
(XII)270899-2-b
(XIV)270899-2-c35211-10-0
(XV)270899-2-c83777-68-8
(I)270899-3-a10316-66-2
(II)270899-3-a10324-65-9
(III)270899-3-a445249-11-6
(IV)270899-3-a23740-37-6
(V)270899-3-a3900-89-8
(VI)270899-3-a2375682-55-4
(VII)270899-3-a2375682-66-7
(VIII)270899-3-a3019-71-4
(IX)270899-3-a2375682-61-2
(XI)270899-3-a2375682-63-4
(I)270899-4-a74-88-4
(II)270899-4-a930-28-9
(III)270899-4-a873-32-5
(V)270899-4-a609-65-4
(VI)270899-4-a142-29-0
(VII)270899-4-a6740-86-9
(VIII)270899-4-a
(IX)270899-4-a
(Xa)270899-4-a1867-66-9
阿伐那非7 steps
Avanafil
CodeCAS No.
AVAN-00187-13-8
AVAN-0022986-19-8
AVAN-00353554-29-3
AVAN-0045909-24-0
AVAN-00541965-95-1
AVAN-006330785-81-4
AVAN-007330785-82-5
AVAN-00823356-96-9
AVAN-009330785-83-6
AVAN-010330785-84-7
AVAN-011372118-67-7
AVAN-012115514-77-7
AVAN-013330786-34-0
AVAN-01475985-45-4
AVAN-0151364671-62-4
AVAN-0161364671-52-2
AVAN-017320407-92-9
AVAN-01871-30-7
AVAN-019
AVAN-0201450983-42-2
AVAN-0211450983-43-3
AVAN-022
AVAN-023a2972-52-3
AVAN-023b55084-66-7
AVAN-023d1534330-76-1
AVAN-023c1534330-77-2
AVAN-024b1534330-75-0
AVAN-024a1534330-72-7
AVAN-024d1534330-74-9
AVAN-025b1534330-73-8
AVAN-024c
AVAN-02662-56-6
AVAN-027
AVAN-028
AVAN-029
AVAN-030
AVAN-031
AVAN-032
AVAN-033
AVAN-034105-56-6
AVAN-03557-13-6
AVAN-03661679-83-2
AVAN-03720187-46-6
AVAN-03813719-57-8
AVAN-039330785-99-4
甲苯磺酸艾多沙班13 steps
Edoxaban Tosilate Hydrate
CodeCAS No.
EDOX-0014771-80-6
EDOX-0025708-19-0
EDOX-003123536-66-3
EDOX-004365997-31-5
EDOX-005365997-32-6
EDOX-006365997-33-7
EDOX-007365997-34-8
EDOX-008
EDOX-009480450-69-9
EDOX-010
EDOX-011
EDOX-012480450-70-2
EDOX-013480450-71-3
EDOX-014
EDOX-015504-24-5
EDOX-01698400-69-2
EDOX-017365996-04-9
EDOX-018273-70-1
EDOX-019259809-24-0
EDOX-02079099-07-3
EDOX-021365996-05-0
EDOX-022365996-06-1
EDOX-023365996-07-2
EDOX-024143150-92-9
EDOX-02570-23-5
EDOX-02622031-64-7
EDOX-027132629-37-9
EDOX-028259809-67-1
EDOX-0291779-49-3
EDOX-030259809-68-2
EDOX-031259809-69-3
EDOX-032259809-70-6
EDOX-033259809-71-7
EDOX-034259809-72-8
EDOX-035259809-73-9
EDOX-036259809-74-0
EDOX-037365998-36-3
EDOX-038480452-36-6
EDOX-039482375-18-8
EDOX-040480449-84-1
EDOX-041365998-33-0
EDOX-042
EDOX-043
米拉贝隆5 steps
Mirabegron
CodeCAS No.
MIRA-00120780-53-4
MIRA-00229968-78-3
MIRA-003223673-34-5
MIRA-004223673-35-6
MIRA-005223673-36-7
MIRA-00629676-71-9
MIRA-0071329485-55-3
MIRA-008611-71-2
MIRA-009521284-19-5
MIRA-010521284-21-9
MIRA-011521284-22-0
MIRA-012100-52-7
MIRA-013211635-75-5
MIRA-014223673-46-9
MIRA-015391901-45-4
MIRA-016104-10-9
MIRA-017104060-23-3
MIRA-018695171-91-6
MIRA-0192549-14-6
MIRA-020
MIRA-02166659-20-9
MIRA-02289336-46-9
MIRA-023211102-84-0
MIRA-024887576-08-1
MIRA-025a26407-07-8
MIRA-025b52273-60-6
MIRA-0261616489-60-1
MIRA-0271616489-61-2
MIRA-028
MIRA-0291616489-66-7
MIRA-030
MIRA-031
MIRA-032
MIRA-033381721-84-2
MIRA-03464220-26-4
MIRA-0351447822-02-7
MIRA-0361447822-04-9
MIRA-0371447822-06-1
MIRA-0381447822-03-8
MIRA-0391447822-05-0
MIRA-0401447822-07-2
MIRA-041
MIRA-042
瑞派替尼7 steps
Ripretinib
CodeCAS No.
DCC-2618
DCC-2618-00117368-12-6
DCC-2618-0022105-61-5
DCC-2618-0031225278-64-7
DCC-2618-0041225278-65-8
DCC-2618-005761446-44-0
DCC-2618-0061225278-35-2
DCC-2618-007113020-21-6
DCC-2618-0081225278-79-4
DCC-2618-0091225278-49-8
DCC-2618-0101225278-16-9
(I)819703-1-a105-50-0
(II)819703-1-a6975-44-6
(III)819703-1-a40296-46-6
(IV)819703-1-a75-04-7
(V)819703-1-a959162-97-1
(VI)819703-1-a959162-99-3
(VII)819703-1-a959163-01-0
(VIII)819703-1-a,(VIII)819703-1-b1442471-26-2
(IX)819703-1-a1442470-52-1
(X)819703-1-a74-89-5
(XIa)819703-1-a1442470-53-2
(XIb)819703-1-a
(XIIa)819703-1-a103-71-9
(XIIb)819703-1-a4930-03-4
(XIII)819703-1-a61150-59-2
(XIV)819703-1-a1012879-09-2
(XV)819703-1-a1012879-10-5
(XVI)819703-1-b192508-36-4
(XVII)819703-1-b858972-16-4
(XVIII)819703-1-b858972-17-5
(I)819703-2-a1807256-54-7
(II)819703-2-a1060809-78-0
(III)819703-2-a
(IV)819703-2-a2766184-37-4
(V)819703-2-a62-53-3
(VI)819703-2-a32315-10-9
(VII)819703-2-a2766184-38-5
(VIII)819703-2-a75-03-6
(IX)819703-2-a1442474-38-5
(III)819703-3-a
拉考沙胺3 steps
Lacosamide
CodeCAS No.
LACO-001312-84-5
LACO-002152612-69-6
LACO-003175481-38-6
LACO-00476-83-5
LACO-005150094-69-2
LACO-006100-46-9
LACO-0071085337-38-7
LACO-0081159573-88-2
LACO-009196601-69-1
LACO-0106368-20-3
LACO-01174-88-4
LACO-01286123-95-7
LACO-01386118-11-8
LACO-014196601-67-9
LACO-0153674-13-3
LACO-016124-41-4
LACO-01765090-78-0
LACO-018705283-58-5
LACO-019262845-82-9
LACO-02017026-42-5
LACO-02124184-43-8
LACO-02218509-25-6
LACO-023353291-72-2
LACO-024103539-32-8
LACO-0251084734-42-8
LACO-026177473-24-4
LACO-0271084734-55-3
LACO-028196601-66-8
LACO-0293945-69-5
LACO-030603-35-0
LACO-03180923-55-3
LACO-032880468-89-3
LACO-03368820-71-3
LACO-0342051583-26-5
Lacosamide175481-36-4
吡仑帕奈6 steps
Perampanel Hydrate
CodeCAS No.
PERAM-0011072-97-5
PERAM-002381233-96-1
PERAM-003381233-75-6
PERAM-00498-80-6
PERAM-005381233-76-7
PERAM-006172732-52-4
PERAM-007381233-77-8
PERAM-008381250-74-4
PERAM-009109-09-1
PERAM-010624-28-2
PERAM-01113472-85-0
PERAM-01217997-47-6
PERAM-013381725-49-1
PERAM-014381233-78-9
PERAM-015381233-79-0
PERAM-016381248-05-1
PERAM-017380917-95-3
PERAM-018380917-96-4
PERAM-0191628-89-3
PERAM-02024244-60-8
PERAM-021381725-50-4
PERAM-022381248-06-2
PERAM-025914918-74-4
PERAM-0261622863-49-3
PERAM-027214360-79-9
PERAM-0281622863-50-6
PERAM-029927-63-9
PERAM-02355676-22-7
PERAM-0241124-29-4
PERAM-03018698-99-2
PERAM-03162-53-3
PERAM-03271732-86-0
PERAM-0331646529-95-4
PERAM-03416179-97-8
罗沙司他9 steps
Roxadustat
CodeCAS No.
ROXA-00137951-15-8
ROXA-00256-40-6
ROXA-003808115-49-3
ROXA-004808115-50-6
ROXA-005808115-51-7
ROXA-006808115-53-9
ROXA-007808115-64-2
ROXA-008808118-41-4
ROXA-009808118-42-5
ROXA-0102462-31-9
ROXA-011808118-43-6
ROXA-01231643-49-9
ROXA-01338791-62-7
ROXA-01421345-01-7
ROXA-015105-34-0
ROXA-0161421312-31-3
ROXA-0171421312-32-4
ROXA-0181421312-33-5
ROXA-0191421312-34-6
ROXA-0201421312-35-7
ROXA-0215680-79-5
ROXA-0221421312-36-8
ROXA-023108-95-2
ROXA-02464169-34-2
ROXA-02557830-14-5
ROXA-0261537180-07-6
ROXA-0271455091-04-9
ROXA-0282645-02-5
ROXA-0291455091-06-1
ROXA-0301455091-10-7
ROXA-03151-80-9
ROXA-0321509958-19-3
ROXA-0331509958-20-6
卡非佐米10 steps
Carfilzomib
CodeCAS No.
CARF-00113139-15-6
CARF-002962-39-0
CARF-00370637-26-2
CARF-00470637-28-4
CARF-005100564-78-1
CARF-006868540-15-2
CARF-007875309-83-4
CARF-0083235-69-6
CARF-009875309-92-5
CARF-010868540-16-3
CARF-011247068-85-5
CARF-01287694-50-6
CARF-013557-93-7
CARF-014247068-81-1
CARF-015247068-82-2
CARF-0162577-90-4
CARF-0175874-73-7
CARF-01890072-18-7
CARF-019868539-96-2
CARF-02079-04-9
CARF-021868540-08-3
CARF-022110-91-8
CARF-0231140908-89-9
CARF-0246638-79-5
CARF-02513291-18-4
CARF-026869487-76-3
CARF-027869487-77-4
CARF-028
CARF-029869487-78-5
CARF-030
CARF-031869487-79-6
托伐普坦4 steps
Tolvaptan
CodeCAS No.
TOLV-001160129-45-3
TOLV-00235675-46-8
TOLV-003137982-91-3
TOLV-004137977-97-0
TOLV-005933-88-0
TOLV-006137973-76-3
TOLV-00791193-23-6
TOLV-0083377-92-2
TOLV-009608139-02-2
TOLV-010804498-94-0
TOLV-011863762-02-1
TOLV-012
TOLV-013
TOLV-014863762-10-1
TOLV-015863762-20-3
TOLV-016863762-24-7
TOLV-017
TOLV-018317374-07-5
TOLV-01996515-79-6
TOLV-020124-02-7
TOLV-0211594771-76-2
TOLV-0221637784-90-7
TOLV-0231637784-91-8
TOLV-0242516-95-2
TOLV-02551282-49-6
TOLV-0265202-89-1
TOLV-027247237-38-3
TOLV-0282969-81-5
TOLV-029247237-43-0
TOLV-0301448365-49-8
TOLV-031193686-76-9
马来酸奈拉替尼3 steps
Neratinib Maleate
CodeCAS No.
NERT-001214476-09-2
NERT-002848133-87-9
NERT-0031056149-69-9
NERT-004848133-88-0
NERT-005524955-09-7
NERT-006619-08-9
NERT-007586-98-1
NERT-008179687-79-7
NERT-009848133-76-6
NERT-010915941-95-6
NERT-011848139-78-6
NERT-0121632473-08-5
NERT-013625-35-4
NERT-014927802-54-8
NERT-0151403831-68-4
NERT-0161403831-69-5
NERT-0171403831-70-8
NERT-0182032-34-0
NERT-0191403831-73-1
NERT-0201403831-74-2
NERT-0211403831-79-7
NERT-0221403831-80-0
NERT-0231257230-74-2
NERT-024121-88-0
NERT-02525351-89-7
NERT-026116496-76-5
NERT-027848655-78-7
NERT-02894-05-3
NERT-029848133-74-4
NERT-030848133-75-5
可美替尼10 steps
Cobimetinib Fumarate
CodeCAS No.
COBI-00118621-18-6
COBI-002128117-22-6
COBI-003105258-93-3
COBI-00475844-69-8
COBI-005934664-27-4
COBI-00639637-99-5
COBI-007934665-53-9
COBI-008934665-55-1
COBI-009934666-39-4
COBI-010934664-19-4
COBI-011934663-52-2
COBI-01261079-72-9
COBI-01329632-74-4
COBI-014391211-97-5
COBI-015675-14-9
COBI-016106565-71-3
COBI-017398489-26-4
COBI-0181597407-55-0
COBI-0191597407-56-1
COBI-0201597407-57-2 (Freebase)
COBI-0211597407-58-3
COBI-0221597407-59-4 (Freebase)
COBI-023109-04-6
COBI-0241415560-24-5
COBI-0251415564-55-4
COBI-0261415560-00-7
COBI-0271799970-85-6
COBI-0281415559-54-4
COBI-029934666-06-5
COBI-030833451-96-0
布瓦西坦4 steps
Brivaracetam
CodeCAS No.
BRIV-001110-62-3
BRIV-002298-12-4
BRIV-00352944-53-3
BRIV-00478920-10-2
BRIV-0057324-11-0
BRIV-006357338-13-7
BRIV-007357336-19-7
BRIV-008357336-20-0
BRIV-0091552-67-6
BRIV-010128013-61-6
BRIV-01189895-19-2
BRIV-012930123-37-8
BRIV-0133196-15-4
BRIV-014
BRIV-0152052297-80-8
BRIV-016357337-00-9
BRIV-017109-67-1
BRIV-018108340-61-0
BRIV-019
BRIV-020941290-02-4
BRIV-021108-59-8
BRIV-022851293-04-4
BRIV-023
BRIV-024851292-98-3
BRIV-025941289-95-8
BRIV-026941290-06-8
BRIV-027941289-99-2
BRIV-028941290-08-0
BRIV-0291822298-86-1
佩米替尼18 steps
Pemigatinib
CodeCAS No.
PEMIGA-001271-63-6
PEMIGA-002504440-63-5
PEMIGA-00355052-28-3
PEMIGA-004651744-48-8
PEMIGA-005958230-19-8
PEMIGA-0061032815-07-8
PEMIGA-0071032815-08-9
PEMIGA-0084394-85-8
PEMIGA-0092382664-55-1
PEMIGA-0102382664-58-4
PEMIGA-0112382664-60-8
PEMIGA-012651734-54-2
PEMIGA-0132382664-61-9
PEMIGA-014109-90-0
PEMIGA-0152382664-64-2
PEMIGA-0161513860-02-0
PEMIGA-017602-94-8
PEMIGA-01836629-42-2
PEMIGA-019122590-82-3
PEMIGA-020651734-52-0
PEMIGA-021651734-53-1
Pemigatinib1513857-77-6
PEMIGA-022915403-16-6
PEMIGA-0231513859-26-1
PEMIGA-0241513857-72-1
PEMIGA-0251513860-01-9
PEMIGA-0261593816-94-4
PEMIGA-027110-91-8
塞普替尼14 steps
Selpercatinib
CodeCAS No.
SELP-0182222653-74-7
SELP-019869494-16-6
SELP-0202222755-94-2
SELP-0212222752-06-7
SELP-02265873-72-5
SELP-00136016-38-3
SELP-002773-64-8
SELP-00336016-39-4
SELP-00436016-40-7
SELP-00550720-12-2
SELP-0061207839-87-9
SELP-007623-47-2
SELP-0081207557-35-4
SELP-0091416439-70-7
SELP-0101207839-86-8
SELP-0112068065-03-0
SELP-0122068065-04-1
SELP-0131822680-43-2
SELP-0142068065-05-2
SELP-015558-30-5
SELP-0162222653-73-6
SELP-017444120-95-0
SELP-0232222756-36-5
SELP-02438254-49-8
SELP-0262222654-09-1
SELP-0272306275-33-0
盐酸鲁拉西酮4 steps
Lurasidone Hydrochloride
CodeCAS No.
LURA-00487691-87-0
LURA-005
LURA-0062054161-88-3
LURA-00171749-03-6
LURA-00265376-05-8
LURA-003186204-35-3
LURA-007110-17-8
LURA-00877-79-2
LURA-00988-98-2
LURA-0101687-30-5
LURA-01158574-95-1
LURA-0122305-32-0
LURA-0131421374-92-6
LURA-0141792220-25-7
LURA-0151421374-93-7
LURA-0161421374-94-8
LURA-018111-42-2
LURA-019
LURA-0201421374-97-1
LURA-0211421374-98-2
LURA-02223031-78-9
LURA-02414805-29-9
LURA-023
恩考芬尼17 steps
Encorafenib
CodeCAS No.
ENCO-001100-52-7
ENCO-00216726-41-3
ENCO-0031086271-92-2
ENCO-004123-06-8
ENCO-0051086250-41-0
ENCO-00689897-29-0
ENCO-0071269440-48-3
ENCO-0081269440-49-4
ENCO-0091269440-51-8
ENCO-01050-01-1
ENCO-0111269440-54-1
ENCO-0121269440-57-4
ENCO-0131269440-58-5
ENCO-0141229025-32-4
ENCO-0151269440-60-9
ENCO-0161269440-69-8
ENCO-0171269440-77-8
ENCO-0181269440-78-9
ENCO-0191269440-99-4
ENCO-0201996-30-1
ENCO-0211269232-93-0
ENCO-0221269232-94-1
ENCO-02373183-34-3
洛拉替尼9 steps
Lorlatinib
CodeCAS No.
LORL-001914225-70-0
LORL-0021454847-96-1
LORL-0031454847-97-2
LORL-00416867-03-1
LORL-0051454847-98-3
LORL-0061454847-99-4
LORL-0071454848-00-0
LORL-0081454848-24-8
LORL-009
LORL-010
LORL-0111454850-15-7
LORL-0125775-89-3
LORL-0131454848-19-1
LORL-01416066-84-5
LORL-0151454848-21-5
LORL-0161454848-22-6
LORL-0171454848-23-7
LORL-0181454848-70-4
LORL-0191454852-76-6
LORL-0201612891-02-7
LORL-0211612891-03-8
LORL-0221612891-04-9
硫酸艾沙康唑17 steps
Isavuconazonium Sulfate
CodeCAS No.
ISAV-00117392-83-5
ISAV-002135206-87-0
ISAV-003135270-08-5
ISAV-004399-94-0
ISAV-005241479-69-6
ISAV-006241479-70-9
ISAV-007288-88-0
ISAV-008241479-71-0
ISAV-009241479-72-1
ISAV-010241479-73-2
ISAV-011241479-74-3
ISAV-012368421-58-3
ISAV-01320099-89-2
ISAV-014241479-67-4
ISAV-015338990-31-1
ISAV-016338990-63-9
ISAV-0172942-59-8
ISAV-01849609-84-9
ISAV-019232951-83-6
ISAV-020338990-70-8
ISAV-02132399-12-5
ISAV-02250893-53-3
泰地唑利磷酸盐7 steps
Tedizolid Phosphate
CodeCAS No.
TEDI-001372-19-0
TEDI-002149524-47-0
TEDI-00360456-26-0
TEDI-004149524-42-5
TEDI-005487041-08-7
TEDI-006856867-57-7
TEDI-007380380-64-3
TEDI-008856866-72-3
TEDI-009624-28-2
TEDI-01097483-77-7
TEDI-011380380-60-9
TEDI-0121261441-79-5
TEDI-013113826-06-5
TEDI-014501939-82-8
TEDI-0151654754-45-6
TEDI-016883231-14-9
TEDI-0171654754-39-8
TEDI-018656-65-5
TEDI-019510729-01-8
TEDI-020874290-59-2
TEDI-0211220910-89-3
TEDI-0221374651-37-2
醋酸伏诺拉生10 steps
Vonoprazan Acetate
CodeCAS No.
VONO-001445-27-2
VONO-002655-15-2
VONO-003105-56-6
VONO-004881673-98-9
VONO-005881674-01-7
VONO-006881674-06-2
VONO-007881674-58-4
VONO-008881674-56-2
VONO-00942899-76-3
VONO-010881677-11-8
VONO-011110-17-8
VONO-012636-73-7
VONO-0131610043-62-3
VONO-0141610043-63-4
VONO-01516133-25-8
VONO-0161831110-76-9
VONO-017
VONO-018
Vonoprazan Fumarate1260141-27-2
VONO-0201240948-77-9
VONO-0211807642-39-2
VONO-0221807642-41-6
维贝格隆9 steps
Vibegron
CodeCAS No.
VIBE-001163625-46-5
VIBE-0022136-75-6
VIBE-0031190391-87-7
VIBE-0041190391-88-8
VIBE-0052767-70-6
VIBE-0061190391-89-9
VIBE-0071190391-90-2
VIBE-0081190391-85-5
VIBE-0091190392-22-3
VIBE-0101190393-25-9
VIBE-011173142-47-7
VIBE-01214735-70-7
VIBE-0131190392-23-4
VIBE-0145390-04-5
VIBE-01529329-03-1
VIBE-0161628836-07-6
VIBE-0171437235-48-7
VIBE-0181437235-52-3
VIBE-019636-98-6
VIBE-0201628836-08-7
VIBE-0211295539-30-8
VIBE-0224931-66-2
卡利拉嗪盐酸盐5 steps
Cariprazine Hydrochloride
CodeCAS No.
CARI-00156961-77-4
CARI-00257260-71-6
CARI-003503315-03-5
CARI-004119532-26-2
CARI-005215790-29-7
CARI-006506427-91-4
CARI-007791778-53-5
CARI-00879-44-7
CARI-00987976-86-1
CARI-0101512029-27-4
CARI-011867-13-0
CARI-0121698050-47-3
CARI-0131642586-63-7
CARI-0141698050-40-6
CARI-0151642586-58-0
CARI-01641202-77-1
CARI-017104-03-0
CARI-018113543-96-7
CARI-019946598-34-1
CARI-020917342-29-1
CARI-0221702725-92-5
阿帕他胺11 steps
Apalutamide
CodeCAS No.
APAL-00122245-83-6
APAL-002887707-23-5
APAL-003887707-25-7
APAL-0042393-23-9
APAL-005956104-44-2
APAL-006956104-45-3
APAL-007573762-62-6
APAL-008951753-87-0
APAL-009915087-26-2
APAL-01072482-64-5
APAL-011948717-18-8
APAL-012956104-46-4
APAL-013915087-25-1
APAL-0141191-95-3
APAL-01565753-47-1
APAL-01699368-66-8
APAL-01799368-67-9
APAL-01899368-68-0
APAL-0191057383-91-1
APAL-0201165744-14-8
替格瑞洛9 steps
Ticagrelor
CodeCAS No.
TICA-001145783-14-8
TICA-002155899-66-4
TICA-003220241-59-8
TICA-004220241-60-1
TICA-005220241-61-2
TICA-006274693-22-0
TICA-00788016-31-3
TICA-008274693-23-1
TICA-009274693-24-2
TICA-010220352-38-5
TICA-011274693-25-3
TICA-01230472-97-0
TICA-013274693-26-4
TICA-01460410-16-4
TICA-01551779-32-9
TICA-016220241-57-6
TICA-0177529-22-8
TICA-018220241-58-7
TICA-01977-76-9
阿伐替尼12 steps
Avapritinib
CodeCAS No.
AVAPR-0151703794-88-0
AVAPR-016888721-83-3
AVAPR-017761446-44-0
AVAPR-0181703794-32-4
Avapritinib
AVAPR-00189793-12-4
AVAPR-00257260-71-6
AVAPR-003253315-69-4
AVAPR-004253315-11-6
AVAPR-0051117-97-1
AVAPR-0061703794-70-0
AVAPR-007352-13-6
AVAPR-0081703794-73-3
AVAPR-0091703795-52-1
AVAPR-0101703794-33-5
AVAPR-0111703794-85-7
AVAPR-012343338-28-3
AVAPR-0131703794-86-8
AVAPR-0141703794-87-9
布瑞哌唑3 steps
Brexpiprazole
CodeCAS No.
BREX-00170500-72-0
BREX-0026940-78-9
BREX-003
BREX-004
BREX-0055118-13-8
BREX-006110-85-0
BREX-007387-45-1
BREX-00857260-71-6
BREX-0091096535-48-6
BREX-010623-51-8
BREX-011
BREX-012
BREX-013
BREX-014141-84-4
BREX-01565562-49-4
BREX-0161420987-77-4
BREX-01723967-57-9
BREX-018
厄达替尼7 steps
Erdafitinib
CodeCAS No.
ERDA-00150998-17-9
ERDA-002761446-44-0
ERDA-0031346245-03-1
ERDA-0041083325-87-4
ERDA-00510272-07-8
ERDA-0061346133-39-8
ERDA-00786864-60-0
ERDA-0081346245-08-6
ERDA-0091346242-78-1
ERDA-0101346245-10-0
Erdafitinib1346242-81-6
ERDA-01155686-94-7
ERDA-0131346245-04-2
ERDA-01420469-65-2
ERDA-0166306-61-2
ERDA-017627-11-2
ERDA-0181021002-43-6
ERDA-0191346245-09-7
阿吡利塞8 steps
Alpelisib
CodeCAS No.
ALPE-001889940-13-0
ALPE-0021163707-53-6
ALPE-0034652-27-1
ALPE-0041357476-64-2
ALPE-0051357476-66-4
ALPE-0061357476-67-5
ALPE-0077336-51-8
ALPE-0081357476-68-6
ALPE-0091357476-69-7
ALPE-0101357476-70-0
ALPE-0117531-52-4
ALPE-0121378865-93-0
ALPE-01378191-00-1
ALPE-0141396893-39-2
ALPE-015128-08-5
ALPE-0161396893-40-5
ALPE-0171396893-41-6
维奈克拉11 steps
Venetoclax
CodeCAS No.
VENE-001183208-35-7
VENE-002858116-66-2
VENE-003685514-01-6
VENE-004106614-28-2
VENE-0051235865-75-4
VENE-0061228780-72-0
VENE-0071235865-76-5
VENE-0081235865-77-6
VENE-0091228779-96-1
VENE-01032767-46-7
VENE-0111228780-46-8
VENE-0121679-18-1
VENE-0131228780-49-1
VENE-0141228780-51-5
VENE-01557260-71-6
VENE-0161228780-71-9
盐酸卡马替尼12 steps
Capmatinib Hydrochloride
CodeCAS No.
CAPMA-001153556-42-4
CAPMA-002695188-21-7
CAPMA-003343564-56-7
CAPMA-004304445-49-6
CAPMA-0051006875-89-3
CAPMA-0061029714-83-7
CAPMA-0071006875-90-6
CAPMA-0082200-97-7
CAPMA-0091029714-84-8
CAPMA-0101029714-85-9
CAPMA-0111029714-86-0
CAPMA-0121029714-87-1
CAPMA-0131029714-88-2
CAPMA-0145332-25-2
CAPMA-015476660-18-1
Capmatinib1029712-80-8
甲苯磺酸奥马环素2 steps
Omadacycline tosylate
CodeCAS No.
OMAD-001389140-04-9
OMAD-002488818-70-8
OMAD-0035813-64-9
OMAD-00413614-98-7
OMAD-005118-29-6
OMAD-006a835877-67-3
OMAD-006b
OMAD-00719532-98-0
OMAD-008a488820-34-4
OMAD-008b835877-68-4
OMAD-009630-19-3
OMAD-010162150-89-2
OMAD-011541-88-8
OMAD-0121075240-46-8
OMAD-0131075240-41-3
OMAD-014
琥珀酸瑞波西利9 steps
Ribociclib Succinate
CodeCAS No.
RIBO-00136082-50-5
RIBO-0021003-03-8
RIBO-003733039-20-8
RIBO-004107-19-7
RIBO-0051374639-76-5
RIBO-0061374639-77-6
RIBO-007124-40-3
RIBO-0081211443-61-6
RIBO-009571188-59-5
RIBO-0101374639-78-7
RIBO-01152092-47-4
RIBO-012110-85-0
RIBO-013775288-71-6
RIBO-014571189-16-7
恩曲替尼11 steps
Entrectinib
CodeCAS No.
ENTR-001461-96-1
ENTR-002218301-22-5
ENTR-0031108745-07-8
ENTR-0041108745-09-0
ENTR-0051108745-11-4
ENTR-0061108745-14-7
ENTR-0071108745-16-9
ENTR-0081108745-18-1
ENTR-009942271-64-9
ENTR-0101108745-20-5
ENTR-0111108745-22-7
ENTR-0121108743-56-1
ENTR-0131108743-96-9
ENTR-01429943-42-8
酒石酸匹莫范色林6 steps
Pimavanserin Tartrate
CodeCAS No.
PIMAV-001123-08-0
PIMAV-00278-77-3
PIMAV-00318962-07-7
PIMAV-004882035-15-6
PIMAV-0054734-09-2
PIMAV-006639863-75-5
PIMAV-007359878-47-0
PIMAV-0081445-73-4
PIMAV-009140-75-0
PIMAV-01056553-60-7
PIMAV-011767-00-0
PIMAV-012177948-43-5
PIMAV-01387120-72-7
PIMAV-014459-57-4
苯磺酸美洛加巴林7 steps
Mirogabalin besilate
CodeCAS No.
MRIO-001106-95-6
MRIO-0031138245-48-3
MRIO-0041138245-49-4
MRIO-00562327-21-3
MRIO-0061138245-50-7
MRIO-0071415817-42-3
MRIO-0081138246-18-0
MRIO-0091138246-20-4
MRIO-0101235479-61-4
MRIO-011105-53-3
MRIO-0121644251-28-4
MRIO-0131644251-34-2
MRIO-0141644251-58-0
MRIO-0151644251-62-6
索格列净11 steps
Sotagliflozin
CodeCAS No.
SOTA-0017296-58-4
SOTA-002114861-22-2
SOTA-0031103738-17-5
SOTA-004110-91-8
SOTA-0051103738-19-7
SOTA-0061103738-29-9
SOTA-0071103738-30-2
SOTA-0081384242-55-0
SOTA-0091384242-56-1
SOTA-0101018899-03-0
SOTA-01119094-56-5
SOTA-012281652-58-2
SOTA-013103-73-1
SOTA-0141103738-26-6
哌柏西利9 steps
Palbociclib
CodeCAS No.
PALB-01257260-71-6
PALB-013571189-16-7
PALB-00136082-50-5
PALB-0021003-03-8
PALB-003733039-20-8
PALB-004107-93-7
PALB-0051013916-37-4
PALB-0061016636-76-2
PALB-007571188-59-5
PALB-008571188-82-4
PALB-009111-34-2
PALB-010866084-31-3
PALB-01139856-50-3
甲磺酸仑伐替尼9 steps
Lenvatinib Mesilate
CodeCAS No.
LENT-00120925-27-3
LENT-0027251-09-4
LENT-00315568-86-2
LENT-004417721-14-3
LENT-005417721-15-4
LENT-006417721-34-7
LENT-007417721-35-8
LENT-008417721-36-9
LENT-00917609-80-2
LENT-010417722-93-1
LENT-0111885-14-9
LENT-012417722-95-3
LENT-01386483-52-5
阿贝西利9 steps
Abemaciclib
CodeCAS No.
ABEM-00175-31-0
ABEM-0021118-69-0
ABEM-00367567-26-4
ABEM-0041231930-29-2
ABEM-0051231930-33-8
ABEM-00673183-34-3
ABEM-0071231930-37-2
ABEM-0082927-71-1
ABEM-0091231930-42-9
ABEM-0101180132-17-5
ABEM-0115308-25-8
ABEM-012149806-06-4
ABEM-0131231930-25-8
曲美替尼10 steps
Trametinib
CodeCAS No.
TRAT-00129632-74-4
TRAT-00286483-52-5
TRAT-003871700-18-4
TRAT-004372-09-8
TRAT-005871700-26-4
TRAT-006871700-28-6
TRAT-007871700-30-0
TRAT-008871700-22-0
TRAT-009516-05-2
TRAT-010871700-24-2
TRAT-011871700-32-2
TRAT-012102-28-3
TRAT-013871700-25-3
硫酸氢司美替尼11 steps
Selumetinib sulfate
CodeCAS No.
SELT-00161079-72-9
SELT-002197520-71-1
SELT-003284030-57-5
SELT-004284030-58-6
SELT-00562-53-3
SELT-006606093-58-7
SELT-007606093-59-8
SELT-008606143-93-5
SELT-009606143-46-8
SELT-010606144-02-9
SELT-011606144-04-1
SELT-012391212-29-6
SELT-013606144-05-2
利伐沙班9 steps
Rivaroxaban
CodeCAS No.
RIVA-001141-43-5
RIVA-00279-04-9
RIVA-0046320-16-7
RIVA-005109-11-5
RIVA-006350-46-9
RIVA-007446292-04-2
RIVA-008438056-69-0
RIVA-009161596-47-0
RIVA-010446292-07-5
RIVA-011446292-08-6
RIVA-0121430407-73-0
RIVA-01342518-98-9
阿来替尼盐酸盐10 steps
Alectinib Hydrochloride
CodeCAS No.
ALEC-0014133-34-0
ALEC-0021865-83-4
ALEC-0031256578-99-0
ALEC-00417672-26-3
ALEC-0051256579-00-6
ALEC-0061256579-03-9
ALEC-0071256579-06-2
ALEC-0081256579-48-2
ALEC-00953617-35-9
ALEC-0101256579-62-0
ALEC-01189343-06-6
ALEC-0121256580-24-1
泽布替尼10 steps
Zanubrutinib
CodeCAS No.
ZANU-0012215-77-2
ZANU-0021623-95-6
ZANU-003330792-68-2
ZANU-004330792-69-3
ZANU-005330792-70-6
ZANU-006960201-86-9
ZANU-0072190506-55-7
ZANU-0082190506-56-8
ZANU-0091633350-03-4
ZANU-0101633350-05-6
ZANU-0111633350-06-7
Zanubrutinib1691249-45-2
伐度司他5 steps
Vadadustat
CodeCAS No.
VADA-00185331-33-5
VADA-00263503-60-6
VADA-0031415226-38-8
VADA-0041415226-39-9
VADA-0051415226-40-2
VADA-0065680-79-5
VADA-0071000024-87-2
VADA-0081000025-92-2
VADA-0091956307-64-4
VADA-0101000025-94-4
VADA-0111000025-95-5
VADA-0121000025-96-6
瑞卢戈利9 steps
Relugolix
CodeCAS No.
RELU-001174072-89-0
RELU-002308831-93-8
RELU-003697-73-4
RELU-004308831-94-9
RELU-005308831-95-0
RELU-006308832-01-1
RELU-007577780-07-5
RELU-008737789-92-3
RELU-009737789-93-4
RELU-0105469-69-2
RELU-011737789-61-6
RELU-01250893-53-3
德拉沙星4 steps
Delafloxacin
CodeCAS No.
DELAF-001446-17-3
DELAF-00298349-24-7
DELAF-003247069-27-8
DELAF-004875712-88-2
DELAF-00518621-18-6
DELAF-006
DELAF-007101987-86-4
DELAF-008101987-87-5
DELAF-009339591-73-0
DELAF-010
DELAF-011
DELAF-012
芦曲泊帕7 steps
Lusutrombopag
CodeCAS No.
LUSU-001267651-23-0
LUSU-002952103-45-6
LUSU-003638-45-9
LUSU-0041110767-94-6
LUSU-00567442-07-3
LUSU-0061110767-96-8
LUSU-00762-56-6
LUSU-0081110767-98-0
LUSU-0091110767-89-9
LUSU-0101110768-00-7
LUSU-011153203-80-6
LUSU-0123699-66-9
甲磺酸达拉非尼6 steps
Dabrafenib Mesylate
CodeCAS No.
DABF-0011567366-22-6
DABF-00260230-36-6
DABF-0031567366-18-0
DABF-005630-22-8
DABF-0061567366-20-4
DABF-0071567366-21-5
DABF-0081195768-18-3
DABF-0091195768-19-4
DABF-01013036-57-2
DABF-0111195768-20-7
DABF-0121622082-84-1
DABF-0131195768-23-0
恩格列净8 steps
Empagliflozin
CodeCAS No.
EMPA-00121739-92-4
EMPA-002100-66-3
EMPA-003333361-49-2
EMPA-004333361-51-6
EMPA-005864070-18-8
EMPA-006864070-19-9
EMPA-00732384-65-9
EMPA-0081204220-63-2
EMPA-009864070-37-1
EMPA-010219823-47-9
EMPA-01190-80-2
甲磺酸奥希替尼7 steps
Osimertinib Mesylate
CodeCAS No.
OSIM-001120-72-9
OSIM-0023934-20-1
OSIM-003945016-63-7
OSIM-0041032452-86-0
OSIM-0051075705-01-9
OSIM-0061421372-94-2
OSIM-007142-25-6
OSIM-0081421372-67-9
OSIM-0091421372-66-8
OSIM-010814-68-6
OSIM-01175-75-2
伊布替尼8 steps
Ibrutinib
CodeCAS No.
IBRT-0012215-77-2
IBRT-002330792-68-2
IBRT-003330792-69-3
IBRT-004330792-70-6
IBRT-005330786-24-8
IBRT-006143900-44-1
IBRT-0071022150-11-3
IBRT-008814-68-6
IBRT-0092380-63-4
IBRT-010151266-23-8
IBRT-01151067-38-0
苹果酸卡博替尼7 steps
Cabozantinib S-malate
CodeCAS No.
CABO-0011131-62-0
CABO-0024101-32-0
CABO-0034101-30-8
CABO-004109-94-4
CABO-00513425-93-9
CABO-006849217-54-5
CABO-007849217-60-3
CABO-008598-10-7
CABO-009371-40-4
CABO-010849217-48-7
CABO-011123-30-8
阿可替尼8 steps
Acalabrutinib
CodeCAS No.
ACAT-00155557-52-3
ACAT-002939412-86-9
ACAT-0031148-11-4
ACAT-0041418307-17-1
ACAT-0051418307-18-2
ACAT-0061420478-87-0
ACAT-0071420478-88-1
ACAT-008850568-25-1
ACAT-0091420478-89-2
ACAT-0101420478-90-5
ACAT-011590-93-2
图卡替尼8 steps
Tucatinib
CodeCAS No.
IRBIN-00117420-30-3
IRBIN-0021203904-18-0
IRBIN-0032131230-48-1
IRBIN-004124-68-5
IRBIN-0051429755-57-6
IRBIN-006937263-71-3
IRBIN-0071429755-58-7
IRBIN-008864244-98-4
IRBIN-009
IRBIN-010937263-44-0
Irbinitinib937263-43-9
马来酸阿伐曲泊帕7 steps
Avatrombopag Maleate
CodeCAS No.
AVAT-00134730-20-6
AVAT-002677007-73-7
AVAT-00362-56-6
AVAT-004570407-10-2
AVAT-00517766-28-8
AVAT-006570407-42-0
AVAT-00741667-95-2
AVAT-008570403-04-2
AVAT-0091126-09-6
AVAT-010570403-14-4
AVAT-011110-16-7
奥拉帕利6 steps
Olaparib
CodeCAS No.
OLAP-00116859-59-9
OLAP-002868-85-9
OLAP-00361260-15-9
OLAP-004218301-22-5
OLAP-005763114-25-6
OLAP-006763114-26-7
OLAP-00757260-71-6
OLAP-008763114-04-1
OLAP-009763111-47-3
OLAP-0104023-34-1
贝曲沙班4 steps
Betrixaban
CodeCAS No.
BETR-0011882-69-5
BETR-0021072-98-6
BETR-003280773-16-2
BETR-004585544-20-3
BETR-0056068-72-0
BETR-006330942-01-3
BETR-007619-65-8
BETR-0081129-35-7
BETR-009764659-41-8
BETR-010210963-78-3
苯磺酸瑞马唑仑6 steps
Remimazolam Besilate
CodeCAS No.
REMIB-0015794-88-7
REMIB-002109-04-6
REMIB-0031563-56-0
REMIB-004145038-50-2
REMIB-005
REMIB-006308242-23-1
REMIB-0077264-90-6
REMIB-0081275616-60-8
REMIB-0092799-16-8
REMIB-0101275616-59-5
阿哌沙班6 steps
Apixaban
CodeCAS No.
APIX-001540-37-4
APIX-0024509-90-4
APIX-003385425-15-0
APIX-004545445-10-1
APIX-005473927-69-4
APIX-00627143-07-3
APIX-007473927-64-9
APIX-008675-20-7
APIX-009503614-91-3
甲苯磺酸卢美哌隆7 steps
Lumateperone tosylate
CodeCAS No.
LUMAT-00159564-59-9
LUMAT-00253374-52-0
LUMAT-00329976-53-2
LUMAT-004313544-31-9
LUMAT-005313369-16-3
LUMAT-006313369-25-4
LUMAT-007313369-26-5
LUMAT-008313368-85-3
LUMAT-0093874-54-2
达罗他胺6 steps
Darolutamide
CodeCAS No.
ODM-201-001154607-01-9
ODM-201-002903550-26-5
ODM-201-0031297537-35-9
ODM-201-0041297537-39-3
ODM-201-0051297537-37-1
ODM-201-00679069-13-9
ODM-201-0071297537-41-7
ODM-201-0081297537-45-1
ODM-201-0091297537-33-7
恩扎卢胺5 steps
Enzalutamide
CodeCAS No.
ENZA-0011427-07-2
ENZA-002403-24-7
ENZA-003915087-24-0
ENZA-004915087-25-1
ENZA-00575-86-5
ENZA-006915087-32-0
ENZA-007143782-23-4
阿普米司特5 steps
Apremilast
CodeCAS No.
APER-0011131-52-8
APER-002253168-94-4
APER-0031188-21-2
APER-004608141-43-1
APER-0056296-53-3
APER-006603-11-2
APER-0075434-20-8
利格列汀4 steps
Linagliptin
CodeCAS No.
LINA-00193703-24-3
LINA-0023355-28-0
LINA-003666816-98-4
LINA-004109113-72-6
LINA-005853029-57-9
LINA-006309956-78-3
LINA-007668273-75-4
塞利尼索5 steps
Selinexor
CodeCAS No.
SELI-00127126-93-8
SELI-002317319-15-6
SELI-0031333154-10-1
SELI-0041388842-43-0
SELI-0051421923-95-6
SELI-0061388842-44-1
SELI-00754608-52-5
枸橼酸托法替布4 steps
Tofacitinib Citrate
CodeCAS No.
TOFA-00132018-96-5
TOFA-002384338-23-2
TOFA-0033680-69-1
TOFA-004384337-90-0
TOFA-005384336-73-6
TOFA-00616130-58-8
磷酸芦可替尼5 steps
Ruxolitinib Phosphate
CodeCAS No.
RUXO-0013680-69-1
RUXO-002941685-26-3
RUXO-003269410-08-4
RUXO-004941685-27-4
RUXO-005591769-05-0
RUXO-006941685-40-1
比克替拉韦4 steps
Bictegravir
CodeCAS No.
BICTE-0011335210-23-5
BICTE-0021616340-75-0
BICTE-0031110772-05-8
BICTE-005214759-21-4
-1611493-60-7
达普司他3 steps
Daprodustat
CodeCAS No.
DAPR-001538-75-0
DAPR-002141-82-2
DAPR-00335824-91-0
DAPR-0042949-22-6
DAPR-005960540-96-9
乌帕替尼3 steps
Upadacitinib
CodeCAS No.
ABT-494-0011708997-42-5
ABT-494-0021428243-28-0
ABT-494-003753-90-2
舒更葡糖钠2 steps
Sugammadex Sodium
CodeCAS No.
SUGA-001
SUGA-002
替尔泊肽18 steps
Tirzepatide
CodeCAS No.
-71989-33-8
非达霉素1 steps
Fidaxomicin
CodeCAS No.
FIDA-001

Tier B — Position early

DrugGeneric nameOriginatorFirst approvalExpiryPeak($B)StepsInterm.
替尔泊肽Tirzepatide礼来制药2022203636.51▲181
比克替拉韦BictegravirGilead Inc-203312*45
乌帕替尼UpadacitinibAbbott Laboratories201920338.3▲33
维奈克拉Venetoclax艾伯维201620302.79▲1116
达罗他胺Darolutamide芬兰奥立安集团201920312.7▲69
枸橼酸托法替布Tofacitinib Citrate辉瑞201220282.46▲46
阿普米司特Apremilast新基公司201420282.29▲57
甲磺酸达拉非尼Dabrafenib Mesylate葛兰素史克201320292.21▲612
盐酸鲁拉西酮Lurasidone Hydrochloride大日本住友201020281.95▲423
拉考沙胺Lacosamide比利时优时比制药有限公司200820281.92▲335
阿来替尼盐酸盐Alectinib Hydrochloride中外制药株式会社201420301.89▲1012
舒更葡糖钠Sugammadex SodiumMerck & Co Inc200820281.84▲22
托伐普坦TolvaptanOtsuka Holdings Co Ltd200920281.84▲431
甲苯磺酸艾多沙班Edoxaban Tosilate Hydrate第一三共株式会社201120281.79▲1343
盐酸艾司氯胺酮Esketamine Hydrochloride辉瑞199720291.7▲346
替格瑞洛Ticagrelor阿斯利康201020291.59▲919
卡非佐米CarfilzomibOnyx Pharmaceuticals Inc201220291.57▲1031
米拉贝隆Mirabegron安斯泰来制药集团201120291.54▲543
卡格列净/盐酸二甲双胍Canagliflozin/Metformin Hydrochloride强生创新制药201420291.11▲-0
苹果酸卡博替尼Cabozantinib S-malateExelixis Inc201220291.03▲711
洛拉替尼Lorlatinib辉瑞201820301.02▲922

Tier C — Watch / fast-turnover trade

非奈利酮（Finerenone）、布瓦西坦（Brivaracetam）、塞普替尼（Selpercatinib）、恩考芬尼（Encorafenib）、甲苯磺酸卢美哌隆（Lumateperone tosylate）、利格列汀（Linagliptin）、硫酸氢司美替尼（Selumetinib sulfate）、马来酸阿伐曲泊帕（Avatrombopag Maleate）、酒石酸匹莫范色林（Pimavanserin Tartrate）、阿吡利塞（Alpelisib）、恩曲替尼（Entrectinib）、醋酸伏诺拉生（Vonoprazan Acetate）、维贝格隆（Vibegron）、图卡替尼（Tucatinib）、苯磺酸美洛加巴林（Mirogabalin besilate）、阿伐替尼（Avapritinib）、硫酸艾沙康唑（Isavuconazonium Sulfate）、非达霉素（Fidaxomicin）、罗沙司他（Roxadustat）、普拉替尼（Pralsetinib）、瑞派替尼（Ripretinib）、塞利尼索（Selinexor）、苯磺酸瑞马唑仑（Remimazolam Besilate）、索格列净（Sotagliflozin）、瑞卢戈利（Relugolix）、厄达替尼（Erdafitinib）、吡仑帕奈（Perampanel Hydrate）、马来酸奈拉替尼（Neratinib Maleate）、泰地唑利磷酸盐（Tedizolid Phosphate）、可美替尼（Cobimetinib Fumarate）、盐酸卡马替尼（Capmatinib Hydrochloride）、曲美替尼（Trametinib）、甲苯磺酸奥马环素（Omadacycline tosylate）、艾拉环素（Eravacycline）、佩米替尼（Pemigatinib）、达普司他（Daprodustat）、阿伐那非（Avanafil）、伐度司他（Vadadustat）、德拉沙星（Delafloxacin）、贝曲沙班（Betrixaban）、芦曲泊帕（Lusutrombopag）

Data notes

  • Sales column: ▲ = Pharmacodia-observed global peak sales, * = public estimate, blank = no sales data. The API returns no unit; calibrated against six drugs versus public revenue (ratio ≈1000–1100), so the unit is taken to be USD million.
  • Expiry years are public compound/core patent expiries (US), not yet from the Pharmacodia patent library: its patent endpoint returns 401 'authentication required' for the current session.
  • Semaglutide matched a Hybio (Shenzhen) entry rather than the Novo Nordisk originator; no route retrieved.
  • Dapagliflozin / canagliflozin matched metformin combination products, not the single agent.
  • Monoclonal antibodies fall outside Pharmacodia's default search scope (chemical-drug library); biologics have no synthetic intermediate chain anyway.

Source：Pharmacodia（药渡）授权账号查询 · 窗口 2028-2033 · 生成于 2026-09-17 · Sales unit: USD million (inferred)