Finerenone
Chronic kidney disease (CKD) associated with type 2 diabetes; slows renal function decline and cardiovascular events
- CAS No.
- 1050477-31-0
- Indication Class
- Cardiovascular / Renal
- Patent Expiry
- To be assessed
- Therapeutic Area
- Cardio-Renal Metabolism
- Target / Mechanism
- NR3C2
- Labeled Purity
- 99%+
- Registration Readiness
- GMP/DMF
- Commercialization Tier
- API (Commercialized)
- Linked Intermediates
- 6 key intermediates available
Key Intermediates for This API
Order: listed intermediates that accept enquiries first; fragments shared across several APIs rank higher| Intermediate | CAS | Shared | Action |
|---|---|---|---|
| 2-chloro-5-methylpyridin-4-amine | 79055-62-2 | — | |
| 2-Cyanoethyl 3-oxobutanoate | 65193-87-5 | — | |
| 2-cyanoethyl 4-(4-cyano-2-methoxyphenyl)-2,8-dimethyl-5-oxo-1,4,5,6-tetrahydro-1,6-naphthyridine-3-carboxylate | 1050477-43-4 | — | |
| 4-AMino-5-Methylpyridin-2-ol | 95306-64-2 | — | |
| 4-Bromo-2-methoxybenzaldehyde | 43192-33-2 | — | |
| 4-formyl-3-methoxybenzonitrile | 21962-45-8 | — |
Listing Logic · Why It's Worth Listing
The first nonsteroidal mineralocorticoid receptor antagonist (nsMRA), filling an anti-inflammatory and anti-fibrotic gap in diabetic kidney disease and recommended by major guidelines, a clearly incremental new product.
Cardio-Renal Metabolism · Marketed; available for immediate sourcing
GMP/DMF-ready; supports regulatory filing and audit in target markets
6 key intermediates available; scale-up and cost control manageable
Product Description
Finerenone is a prescription medication used to protect the heart and kidneys in adults with chronic kidney disease (CKD) associated with type 2 diabetes. It represents a significant advancement in treatment for these interconnected conditions.
Supply source: Unibest · Finerenone, sourced, vetted and delivered by Unibest. Therapeutic area, indication and listing rationale are qualitative summaries based on public drug knowledge for business reference; actual registration availability and quality specifications are subject to DMF/GMP documentation and the technical agreement confirmed at order.