API (Commercialized)GMP/DMFAnti-infective / Transplant

Letermovir

Prophylaxis of cytomegalovirus (CMV) infection in adult recipients of allogeneic hematopoietic stem cell transplant

CAS No.: 917389-32-3
Indication Class: Anti-infectives
Patent Expiry: Off-patent · 2026 (indicative)
Therapeutic Area: Anti-infective / Transplant
Labeled Purity: 98%+
Registration Readiness: GMP/DMF
Commercialization Tier: API (Commercialized)
Linked Intermediates: 4 key intermediates available
Patent Scope: US / EU compound patent

First-in-class CMV Terminase InhibitorTransplant Specialty

Enquire by CAS All intermediates →

Key Intermediates for This API

Order: listed intermediates that accept enquiries first; fragments shared across several APIs rank higher

Intermediate	CAS	Shared
1-(3-Methoxyphenyl)Piperazine Hydrochloride	16015-70-6	—
2-(8-fluoro-3-(2-methoxy-5-(trifluoromethyl)phenyl) -2-oxo-1,2,3,4-tetrahydroquinazolin-4-yl) acetic acid methyl ester	917389-21-0	—
2-Propenoic acid, 3-[3-fluoro-2-[(phenoxycarbonyl)amino]phenyl]-, methyl ester, (2E)-	1791412-01-5	—
2-Propenoic acid, 3-[3-fluoro-2-[[[[2-methoxy-5-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenyl]-, methyl ester, (2E)-	917389-26-5	—

Listing Logic · Why It's Worth Listing

A first-in-class CMV terminase inhibitor replacing older ganciclovir-class agents with a better safety profile; a niche, high-value specialty API with limited competition.

Demand

Anti-infective / Transplant · Marketed; available for immediate sourcing

Compliance

GMP/DMF-ready; supports regulatory filing and audit in target markets

Supply

4 key intermediates available; scale-up and cost control manageable

Product Description

Letermovir is a first-in-class antiviral medication designed to prevent cytomegalovirus (CMV) infection in adults who have received an allogeneic hematopoietic stem cell transplant (HSCT).

Supply source: Unibest · Letermovir, sourced, vetted and delivered by Unibest. Therapeutic area, indication and listing rationale are qualitative summaries based on public drug knowledge for business reference; actual registration availability and quality specifications are subject to DMF/GMP documentation and the technical agreement confirmed at order.